Publications
Selected papers
Ayuso-García P, Sánchez-Rueda A, Velasco-Avilés S, Tamayo-Caro M, Ferrer- Pinós A, Huarte-Sebastian C, Alvarez V, Riobello C, Jiménez-Vega S, Buendia I, Cañas-Martin J, Fernández-Susavila H, Aparicio-Rey A, Esquinas-Román EM, Ponte CR, Guhl R, Laville N, Pérez-Andrés E, Lavín JL, González-Lopez M, Cámara NM, Aransay AM, Lozano JJ, Sutherland JD, Barrio R, Martinez-Chantar ML, Azkargorta M, Elortza F, Soriano-Navarro M, Matute C, Sánchez-Gómez MV, Bayón-Cordero L, Pérez-Samartín A, Bravo SB, Kurz T, Lama-Díaz T, Blanco MG, Haddad S, Record CJ, van Hasselt PM, Reilly MM, Varela-Rey M, Woodhoo A. Neddylation orchestrates the complex transcriptional and posttranscriptional program that drives Schwann cell myelination. Sci Adv. 2024 Apr 12;10(15):eadm7600. doi: 10.1126/sciadv.adm7600. Epub 2024 Apr 12. PMID: 38608019; PMCID: PMC11014456.
Bonifazi G, Luchena C, Gaminde-Blasco A, Ortiz-Sanz C, Capetillo-Zarate E, Matute C, Alberdi E, De Pittà M. A nonlinear meccano for Alzheimer's emergence by amyloid β-mediated glutamatergic hyperactivity. Neurobiol Dis. 2024 May;194:106473. doi: 10.1016/j.nbd.2024.106473. Epub 2024 Mar 15. PMID: 38493903.
Dakterzada F, Cipriani R, López-Ortega R, Arias A, Riba-Llena I, Ruiz-Julián M, Huerto R, Tahan N, Matute C, Capetillo-Zarate E, Piñol-Ripoll G. Assessment of the Correlation and Diagnostic Accuracy between Cerebrospinal Fluid and
Plasma Alzheimer's Disease Biomarkers: A Comparison of the Lumipulse and Simoa Platforms. Int J Mol Sci. 2024 Apr 23;25(9):4594. doi: 10.3390/ijms25094594. PMID: 38731812; PMCID: PMC11083365.
López-Muguruza E, Matute C. Alterations of Oligodendrocyte and Myelin Energy Metabolism in Multiple Sclerosis. Int J Mol Sci. 2023 Aug 18;24(16):12912. doi: 10.3390/ijms241612912. PMID: 37629092; PMCID: PMC10454078.
Capelo-Diz A, Lachiondo-Ortega S, Fernández-Ramos D, Cañas-Martín J, Goikoetxea-Usandizaga N, Serrano-Maciá M, González-Rellan MJ, Mosca L, Blazquez- Vicens J, Tinahones-Ruano A, Fondevila MF, Buyan M, Delgado TC, Gutierrez de Juan V, Ayuso-García P, Sánchez-Rueda A, Velasco-Avilés S, Fernández-Susavila H, Riobello-Suárez C, Dziechciarz B, Montiel-Duarte C, Lopitz-Otsoa F, Bizkarguenaga M, Bilbao-García J, Bernardo-Seisdedos G, Senra A, Soriano-Navarro
M, Millet O, Díaz-Lagares Á, Crujeiras AB, Bao-Caamano A, Cabrera D, van Liempd S, Tamayo-Carro M, Borzacchiello L, Gomez-Santos B, Buqué X, Sáenz de Urturi D, González-Romero F, Simon J, Rodríguez-Agudo R, Ruiz A, Matute C, Beiroa D, Falcon-Perez JM, Aspichueta P, Rodríguez-Cuesta J, Porcelli M, Pajares MA, Ameneiro C, Fidalgo M, Aransay AM, Lama-Díaz T, Blanco MG, López M, Villa- Bellosta R, Müller TD, Nogueiras R, Woodhoo A, Martínez-Chantar ML, Varela-Rey M. Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting. Cell Metab. 2023 Aug 8;35(8):1373-1389.e8. doi: 10.1016/j.cmet.2023.07.002. Epub 2023 Jul 31. PMID: 37527658; PMCID:
PMC10432853.
Aguado L, Joya A, Garbizu M, Plaza-García S, Iglesias L, Hernández MI, Ardaya M, Mocha N, Gómez-Vallejo V, Cossio U, Higuchi M, Rodríguez-Antigüedad A, Freijo MM, Domercq M, Matute C, Ramos-Cabrer P, Llop J, Martín A. Therapeutic effect of nicotinic receptor activation after ischemic stroke in rats. J Cereb Blood Flow Metab. 2023 Aug;43(8):1301-1316. doi: 10.1177/0271678X231161207. Epub 2023 Mar 13. PMID: 36916034; PMCID: PMC10369150.
Alanko V, Gaminde-Blasco A, Quintela-López T, Loera-Valencia R, Solomon A, Björkhem I, Cedazo-Minguez A, Maioli S, Tabacaru G, Latorre-Leal M, Matute C, Kivipelto M, Alberdi E, Sandebring-Matton A. 27-hydroxycholesterol promotes
oligodendrocyte maturation: Implications for hypercholesterolemia-associated brain white matter changes. Glia. 2023 Jun;71(6):1414-1428. doi: 10.1002/glia.24348. Epub 2023 Feb 13. PMID: 36779429.
Montilla A, Zabala A, Er-Lukowiak M, Rissiek B, Magnus T, Rodriguez-Iglesias N, Sierra A, Matute C, Domercq M. Microglia and meningeal macrophages depletion delays the onset of experimental autoimmune encephalomyelitis. Cell Death Dis. 2023 Jan 12;14(1):16. doi: 10.1038/s41419-023-05551-3. PMID: 36635255; PMCID: PMC9835747.
Manterola A, Chara JC, Aguado T, Palazuelos J, Matute C, Mato S. Cannabinoid CB receptor expression in oligodendrocyte progenitors of the hippocampus revealed by the NG2-EYFP-knockin mouse. Front Neuroanat. 2022 Oct 28;16:1030060. doi: 10.3389/fnana.2022.1030060. PMID: 36387996; PMCID: PMC9650068.
Baraibar AM, Belisle L, Marsicano G, Matute C, Mato S, Araque A, Kofuji P. Spatial organization of neuron-astrocyte interactions in the somatosensory cortex. Cereb Cortex. 2023 Apr 4;33(8):4498-4511. doi: 10.1093/cercor/bhac357. PMID: 36124663; PMCID: PMC10110431.
Ortiz-Sanz C, Balantzategi U, Quintela-López T, Ruiz A, Luchena C, Zuazo-Ibarra J, Capetillo-Zarate E, Matute C, Zugaza JL, Alberdi E. Amyloid β / PKC-dependent alterations in NMDA receptor composition are detected in early stages of Alzheimer´s disease. Cell Death Dis 2022; 13: 253. Link.
Ramos-Gonzalez P, Mato S, Chara JC, Verkhratsky A, Matute C, Cavaliere F. Astrocytic atrophy as a pathological feature of Parkinson’s disease with LRRK2 mutation. NPJ Parkinsons Dis 2021; 7: 31. Link.
Ruiz A, Quintela-López T, Sánchez-Gómez MV, Gaminde-Blasco A, Alberdi E, Matute C. Mitochondrial division inhibitor 1 disrupts oligodendrocyte Ca2+ homeostasis and mitochondrial function. Glia 2020; 68: 1743–1756. Link.
Matute C, Palma A, Serrano-Regal MP, Maudes E, Barman S, Sánchez-Gómez MV, Domercq M, Goebels N, Dalmau J. N-Methyl-D-Aspartate Receptor Antibodies in Autoimmune Encephalopathy Alter Oligodendrocyte Function. Ann Neurol 2020; 87: 670–676. Link.
Serrano-Regal MP, Luengas-Escuza I, Bayón-Cordero L, Ibarra-Aizpurua N, Alberdi E, Pérez-Samartín A, Matute C, Sánchez-Gómez MV. Oligodendrocyte Differentiation and Myelination Is Potentiated via GABAB Receptor Activation. Neuroscience 2020; 439: 163–180. Link.
Quintela-López T, Ortiz-Sanz C, Serrano-Regal MP, Gaminde-Blasco A, Valero J, Baleriola J, Sánchez-Gómez MV, Matute C, Alberdi E. Aβ oligomers promote oligodendrocyte differentiation and maturation via integrin β1 and Fyn kinase signaling. Cell Death Dis 2019; 10: 445. Link.
Zabala A, Vazquez‐Villoldo N, Rissiek B, Gejo J, Martin A, Palomino A, Perez‐Samartín A, Pulagam KR, Lukowiak M, Capetillo‐Zarate E, Llop J, Magnus T, Koch‐Nolte F, Rassendren F, Matute C, Domercq M. P2X4 receptor controls microglia activation and favors remyelination in autoimmune encephalitis. EMBO Mol Med 2018; 10. Link.
Popov A, Brazhe N, Morozova K, Yashin K, Bychkov M, Nosova O, Sutyagina O, Brazhe A, Parshina E, Li L, Medyanik I, Korzhevskii DE, Shenkarev Z, Lyukmanova E, Verkhratsky A, Semyanov A. Mitochondrial malfunction and atrophy of astrocytes in the aged human cerebral cortex. Nat Commun. 2023 Dec 16;14(1):8380. doi: 10.1038/s41467-023-44192-0. PMID: 38104196; PMCID: PMC10725430.
Jiang S, Li X, Li Y, Chang Z, Yuan M, Zhang Y, Zhu H, Xiu Y, Cong H, Yin L, Yu ZW, Fan J, He W, Shi K, Tian DC, Zhang J, Verkhratsky A, Jin WN, Shi FD. APOE from patient-derived astrocytic extracellular vesicles alleviates neuromyelitis optica spectrum disorder in a mouse model. Sci Transl Med. 2024 Feb 28;16(736):eadg5116. doi: 10.1126/scitranslmed.adg5116. Epub 2024 Feb 28. PMID: 38416841.
Verkhratsky A, Butt A, Li B, Illes P, Zorec R, Semyanov A, Tang Y, Sofroniew MV. Astrocytes in human central nervous system diseases: a frontier for new therapies. Signal Transduct Target Ther. 2023 Oct 13;8(1):396. doi: 10.1038/s41392-023-01628-9. PMID: 37828019; PMCID: PMC10570367.
Lin SS, Zhou B, Chen BJ, Jiang RT, Li B, Illes P, Semyanov A, Tang Y, Verkhratsky A. Electroacupuncture prevents astrocyte atrophy to alleviate depression. Cell Death Dis. 2023 May 29;14(5):343. doi: 10.1038/s41419-023-05839-4. PMID: 37248211; PMCID: PMC10227075.
Yi C, Verkhratsky A, Niu J. Pathological potential of oligodendrocyte precursor cells: terra incognita. Trends Neurosci. 2023 Jul;46(7):581-596. doi: 10.1016/j.tins.2023.04.003. Epub 2023 May 12. PMID: 37183154.
Semyanov A, Verkhratsky A. Astrocytic processes: from tripartite synapses to the active milieu. Trends Neurosci. 2021 Oct;44(10):781-792. doi: 10.1016/j.tins.2021.07.006. Epub 2021 Aug 31. PMID: 34479758.
Full list of publications (last 6 years)
(Last update: Aug 2022)
Serrano-Regal MP, Bayón-Cordero L, Chara Ventura JC, Ochoa-Bueno BI, Tepavcevic V, Matute C, Sánchez-Gómez MV. GABAB receptor agonist baclofen promotes central nervous system remyelination. Glia. 2022 Aug 18.
Bayón-Cordero L, Ochoa-Bueno BI, Ruiz A, Ozalla M, Matute C, Sánchez-Gómez MV. GABA Receptor Agonists Protect From Excitotoxic Damage Induced by AMPA in Oligodendrocytes. Front Pharmacol. 2022 Jul 26;13:897056.
Akwa Y, Di Malta C, Zallo F, Gondard E, Lunati A, Diaz-de-Grenu LZ, Zampelli A, Boiret A, Santamaria S, Martinez-Preciado M, Cortese K, Kordower JH, Matute C, Lozano AM, Capetillo-Zarate E, Vaccari T, Settembre C, Baulieu EE, Tampellini D. Stimulation of synaptic activity promotes TFEB-mediated clearance of pathological MAPT/Tau in cellular and mouse models of tauopathies. Autophagy. 2022 Jul 22:1-18.
Aigrot MS, Barthelemy C, Moyon S, Dufayet-Chaffaud G, Izagirre-Urizar L, Gillet-Legrand B, Tada S, Bayón-Cordero L, Chara JC, Matute C, Cartier N, Lubetzki C, Tepavčević V. Genetically modified macrophages accelerate myelin repair. EMBO Mol Med. 2022 Aug 8;14(8):e14759.
Sánchez-de la Torre A, Aguado T, Huerga-Gómez A, Santamaría S, Gentile A, Chara JC, Matute C, Monory K, Mato S, Guzmán M, Lutz B, Galve-Roperh I, Palazuelos J. Cannabinoid CB1 receptor gene inactivation in oligodendrocyte precursors disrupts oligodendrogenesis and myelination in mice. Cell Death Dis. 2022 Jul 7;13(7):585.
Fernandez-Alvarez M, Atienza M, Zallo F, Matute C, Capetillo-Zarate E, Cantero JL. Linking Plasma Amyloid Beta and Neurofilament Light Chain to Intracortical Myelin Content in Cognitively Normal Older Adults. Front Aging Neurosci. 2022 Jun 17;14:896848.
Ortiz-Sanz C, Llavero F, Zuazo-Ibarra J, Balantzategi U, Quintela-López T, Wyssenbach A, Capetillo-Zarate E, Matute C, Alberdi E, Zugaza JL. Recombinant Integrin β1 Signal Peptide Blocks Gliosis Induced by Aβ Oligomers. Int J Mol Sci. 2022 May 20;23(10):5747.
Luchena C, Zuazo-Ibarra J, Valero J, Matute C, Alberdi E, Capetillo-Zarate E. A Neuron, Microglia, and Astrocyte Triple Co-culture Model to Study Alzheimer's Disease. Front Aging Neurosci. 2022 Apr 14;14:844534.
Palma A, Chara JC, Montilla A, Otxoa-de-Amezaga A, Ruíz-Jaén F, Planas AM, Matute C, Pérez-Samartín A, Domercq M. Clemastine Induces an Impairment in Developmental Myelination. Front Cell Dev Biol. 2022 Mar 17;10:841548.
Arotcarena ML, Soria FN, Cunha A, Doudnikoff E, Prévot G, Daniel J, Blanchard-Desce M, Barthélémy P, Bezard E, Crauste-Manciet S, Dehay B. Acidic nanoparticles protect against α-synuclein-induced neurodegeneration through the restoration of lysosomal function. Aging Cell. 2022 Apr;21(4):e13584.
Calovi S, Soria FN, Tønnesen J. Super-resolution STED microscopy in live brain tissue. Neurobiol Dis. 2021 Aug;156:105420.
Bernal-Chico A, Tepavcevic V, Manterola A, Utrilla C, Matute C, Mato S. Endocannabinoid signaling in brain diseases: Emerging relevance of glial cells. Glia. 2022 Mar 30.
Ortiz-Sanz C, Balantzategi U, Quintela-López T, Ruiz A, Luchena C, Zuazo-Ibarra J, Capetillo-Zarate E, Matute C, Zugaza JL, Alberdi E. Amyloid β / PKC-dependent alterations in NMDA receptor composition are detected in early stages of Alzheimer´s disease. Cell Death Dis. 2022; 13: 253
Murueta-Goyena A, Cipriani R, Carmona-Abellán M, Acera M, Ayo N, Del Pino R, Tijero B, Fernández-Valle T, Gabilondo I, Zallo F, Matute C, Sánchez-Pernaute R, Khurana V, Cavaliere F, Capetillo-Zarate E, Gómez-Esteban JC. Characterization of molecular biomarkers in cerebrospinal fluid and serum of E46K-SNCA mutation carriers. Parkinsonism Relat Disord. 2022 Mar;96:29-35.
Milanesi E, Dobre M, Cucos CA, Rojo AI, Jiménez-Villegas J, Capetillo-Zarate E, Matute C, Piñol-Ripoll G, Manda G, Cuadrado A. Whole Blood Expression Pattern of Inflammation and Redox Genes in Mild Alzheimer's Disease. J Inflamm Res. 2021 Nov 20;14:6085-6102.
Echeazarra L, García Del Caño G, Barrondo S, González-Burguera I, Saumell-Esnaola M, Aretxabala X, López de Jesús M, Borrega-Román L, Mato S, Ledent C, Matute C, Goicolea MA, Sallés J. Fit-for-purpose based testing and validation of antibodies to amino- and carboxy-terminal domains of cannabinoid receptor 1. Histochem Cell Biol. 2021 Nov;156(5):479-502.
Montilla A, Ruiz A, Marquez M, Sierra A, Matute C, Domercq M. Role of Mitochondrial Dynamics in Microglial Activation and Metabolic Switch. Immunohorizons. 2021 Aug 10;5(8):615-626.
Aguado T, Huerga-Gómez A, Sánchez-de la Torre A, Resel E, Chara JC, Matute C, Mato S, Galve-Roperh I, Guzman M, Palazuelos J. Δ9 -Tetrahydrocannabinol promotes functional remyelination in the mouse brain. Br J Pharmacol. 2021 Oct;178(20):4176-4192.
Ramos-Gonzalez P, Mato S, Chara JC, Verkhratsky A, Matute C, Cavaliere F. Astrocytic atrophy as a pathological feature of Parkinson’s disease with LRRK2 mutation. NPJ Parkinsons Dis 2021; 7: 31.
Ordaz RP, Garay E, Limon A, Pérez-Samartín A, Sánchez-Gómez MV, Robles-Martínez L, Cisneros-Mejorado A, Matute C, Arellano RO. GABAA Receptors Expressed in Oligodendrocytes Cultured from the Neonatal Rat Contain α3 and γ1 Subunits and Present Differential Functional and Pharmacological Properties. Mol Pharmacol 2021; 99: 133–146.
Joya A, Ardaya M, Montilla A, Garbizu M, Plaza-García S, Gómez-Vallejo V, Padro D, Gutiérrez JJ, Rios X, Ramos-Cabrer P, Cossío U, Pulagam KR, Higuchi M, Domercq M, Cavaliere F, Matute C, Llop J, Martín A. In vivo multimodal imaging of adenosine A1 receptors in neuroinflammation after experimental stroke. Theranostics 2021; 11: 410–425.
Huerga-Gómez A, Aguado T, Sánchez-de la Torre A, Bernal-Chico A, Matute C, Mato S, Guzmán M, Galve-Roperh I, Palazuelos J. Δ9 -Tetrahydrocannabinol promotes oligodendrocyte development and CNS myelination in vivo. Glia 2021; 69: 532–545.
Delgado D, Bilbao AM, Beitia M, Garate A, Sánchez P, González-Burguera I, Isasti A, López De Jesús M, Zuazo-Ibarra J, Montilla A, Domercq M, Capetillo-Zarate E, García Del Caño G, Sallés J, Matute C, Sánchez M. Effects of Platelet-Rich Plasma on Cellular Populations of the Central Nervous System: The Influence of Donor Age. Int J Mol Sci 2021; 22.
Calovi S, Soria FN, Tønnesen J. Super-resolution STED microscopy in live brain tissue. Neurobiol Dis 2021; 156: 105420.
Soria FN, Miguelez C, Peñagarikano O, Tønnesen J. Current Techniques for Investigating the Brain Extracellular Space. Front Neurosci 2020; 14: 570750.
Soria FN, Paviolo C, Doudnikoff E, Arotcarena M-L, Lee A, Danné N, Mandal AK, Gosset P, Dehay B, Groc L, Cognet L, Bezard E. Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling. Nat Commun 2020; 11: 3440.
Serrano-Regal MP, Luengas-Escuza I, Bayón-Cordero L, Ibarra-Aizpurua N, Alberdi E, Pérez-Samartín A, Matute C, Sánchez-Gómez MV. Oligodendrocyte Differentiation and Myelination Is Potentiated via GABAB Receptor Activation. Neuroscience 2020; 439: 163–180.
Serrano-Regal MP, Bayón-Cordero L, Ordaz RP, Garay E, Limon A, Arellano RO, Matute C, Sánchez-Gómez MV. Expression and Function of GABA Receptors in Myelinating Cells. Front Cell Neurosci 2020; 14: 256.
Ruiz A, Zuazo J, Ortiz-Sanz C, Luchena C, Matute C, Alberdi E. Sephin1 Protects Neurons against Excitotoxicity Independently of the Integrated Stress Response. Int J Mol Sci 2020; 21.
Ruiz A, Quintela-López T, Sánchez-Gómez MV, Gaminde-Blasco A, Alberdi E, Matute C. Mitochondrial division inhibitor 1 disrupts oligodendrocyte Ca2+ homeostasis and mitochondrial function. Glia 2020; 68: 1743–1756.
Ortiz-Sanz C, Gaminde-Blasco A, Valero J, Bakota L, Brandt R, Zugaza JL, Matute C, Alberdi E. Early Effects of Aβ Oligomers on Dendritic Spine Dynamics and Arborization in Hippocampal Neurons. Front Synaptic Neurosci 2020; 12: 2.
Moreno-García Á, Bernal-Chico A, Colomer T, Rodríguez-Antigüedad A, Matute C, Mato S. Gene Expression Analysis of Astrocyte and Microglia Endocannabinoid Signaling during Autoimmune Demyelination. Biomolecules 2020; 10.
Montilla A, Zabala A, Matute C, Domercq M. Functional and Metabolic Characterization of Microglia Culture in a Defined Medium. Front Cell Neurosci 2020; 14: 22.
Montilla A, Mata GP, Matute C, Domercq M. Contribution of P2X4 Receptors to CNS Function and Pathophysiology. Int J Mol Sci 2020; 21.
Matute C, Palma A, Serrano-Regal MP, Maudes E, Barman S, Sánchez-Gómez MV, Domercq M, Goebels N, Dalmau J. N-Methyl-D-Aspartate Receptor Antibodies in Autoimmune Encephalopathy Alter Oligodendrocyte Function. Ann Neurol 2020; 87: 670–676.
Diaz-Aparicio I, Paris I, Sierra-Torre V, Plaza-Zabala A, Rodríguez-Iglesias N, Márquez-Ropero M et al. Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome. J Neurosci 2020; 40: 1453–1482.
Cisneros-Mejorado AJ, Pérez-Samartín A, Domercq M, Arellano RO, Gottlieb M, Koch-Nolte F, Matute C. P2X7 Receptors as a Therapeutic Target in Cerebrovascular Diseases. Front Mol Neurosci 2020; 13: 92.
Bengoa-Vergniory N, Faggiani E, Ramos-Gonzalez P, Kirkiz E, Connor-Robson N, Brown LV et al. CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson’s disease. Nat Commun 2020; 11: 4885.
Barriola S, Pérez-Cerdá F, Matute C, Bribián A, López-Mascaraque L. A Clonal NG2-Glia Cell Response in a Mouse Model of Multiple Sclerosis. Cells 2020; 9.
Ardaya M, Joya A, Padro D, Plaza-García S, Gómez-Vallejo V, Sánchez M, Garbizu M, Cossío U, Matute C, Cavaliere F, Llop J, Martín A. In vivo PET Imaging of Gliogenesis After Cerebral Ischemia in Rats. Front Neurosci 2020; 14: 793.
Quintela-López T, Ortiz-Sanz C, Serrano-Regal MP, Gaminde-Blasco A, Valero J, Baleriola J, Sánchez-Gómez MV, Matute C, Alberdi E. Aβ oligomers promote oligodendrocyte differentiation and maturation via integrin β1 and Fyn kinase signaling. Cell Death Dis 2019; 10: 445.
Domercq M, Matute C. Excitotoxicity therapy for stroke patients still alive. EBioMedicine 2019; 39: 3–4.
Domercq M, Matute C. Targeting P2X4 and P2X7 receptors in multiple sclerosis. Curr Opin Pharmacol 2019; 47: 119–125.
Domercq M, Zabala A, Matute C. Purinergic receptors in multiple sclerosis pathogenesis. Brain Res Bull 2019; 151: 38–45.
Zabala A, Vazquez-Villoldo N, Rissiek B, Gejo J, Martin A, Palomino A, Perez-Samartín A, Pulagam KR, Lukowiak M, Capetillo-Zarate E, Llop J, Magnus T, Koch-Nolte F, Rassendren F, Matute C, Domercq M. P2X4 receptor controls microglia activation and favors remyelination in autoimmune encephalitis. EMBO Mol Med 2018; 10: e8743.
Walker CA, Randolph LK, Matute C, Alberdi E, Baleriola J, Hengst U. Aβ1-42 triggers the generation of a retrograde signaling complex from sentinel mRNAs in axons. EMBO Rep 2018; 19: e45435.
Sánchez-Gómez MV, Serrano MP, Alberdi E, Pérez-Cerdá F, Matute C. Isolation, Expansion, and Maturation of Oligodendrocyte Lineage Cells Obtained from Rat Neonatal Brain and Optic Nerve. Methods Mol Biol 2018; 1791: 95–113.
Ruiz A, Alberdi E, Matute C. Mitochondrial Division Inhibitor 1 (mdivi-1) Protects Neurons against Excitotoxicity through the Modulation of Mitochondrial Function and Intracellular Ca2+ Signaling. Front Mol Neurosci 2018; 11: 3.
Martín A, Domercq M, Matute C. Inflammation in stroke: the role of cholinergic, purinergic and glutamatergic signaling. Ther Adv Neurol Disord 2018; 11: 1756286418774267.
Manterola A, Bernal-Chico A, Cipriani R, Ruiz A, Pérez-Samartín A, Moreno-Rodríguez M, Hsu K-L, Cravatt BF, Brown JM, Rodríguez-Puertas R, Matute C, Mato S. Re-examining the potential of targeting ABHD6 in multiple sclerosis: Efficacy of systemic and peripherally restricted inhibitors in experimental autoimmune encephalomyelitis. Neuropharmacology 2018; 141: 181–191.
Manterola A, Bernal-Chico A, Cipriani R, Canedo-Antelo M, Moreno-García Á, Martín-Fontecha M, Pérez-Cerdá F, Sánchez-Gómez MV, Ortega-Gutiérrez S, Brown JM, Hsu K-L, Cravatt B, Matute C, Mato S. Deregulation of the endocannabinoid system and therapeutic potential of ABHD6 blockade in the cuprizone model of demyelination. Biochem Pharmacol 2018; 157: 189–201.
Luchena C, Zuazo-Ibarra J, Alberdi E, Matute C, Capetillo-Zarate E. Contribution of Neurons and Glial Cells to Complement-Mediated Synapse Removal during Development, Aging and in Alzheimer’s Disease. Mediators Inflamm 2018; 2018: 2530414.
Colás L, Domercq M, Ramos-Cabrer P, Palma A, Gómez-Vallejo V, Padro D, Plaza-García S, Pulagam KR, Higuchi M, Matute C, Llop J, Martín A. In vivo imaging of Α7 nicotinic receptors as a novel method to monitor neuroinflammation after cerebral ischemia. Glia 2018; 66: 1611–1624.
Cisneros-Mejorado A, Gottlieb M, Ruiz A, Chara JC, Pérez-Samartín A, Marambaud P, Matute C. Blockade and knock-out of CALHM1 channels attenuate ischemic brain damage. J Cereb Blood Flow Metab 2018; 38: 1060–1069.
Canedo-Antelo M, Serrano MP, Manterola A, Ruiz A, Llavero F, Mato S, Zugaza JL, Pérez-Cerdá F, Matute C, Sánchez-Gómez MV. Inhibition of Casein Kinase 2 Protects Oligodendrocytes From Excitotoxicity by Attenuating JNK/p53 Signaling Cascade. Front Mol Neurosci 2018; 11: 333.
Bribian A, Pérez-Cerdá F, Matute C, López-Mascaraque L. Clonal Glial Response in a Multiple Sclerosis Mouse Model. Front Cell Neurosci 2018; 12: 375.
Alberdi E, Sánchez-Gómez MV, Ruiz A, Cavaliere F, Ortiz-Sanz C, Quintela-López T, Capetillo-Zarate E, Solé-Domènech S, Matute C. Mangiferin and Morin Attenuate Oxidative Stress, Mitochondrial Dysfunction, and Neurocytotoxicity, Induced by Amyloid Beta Oligomers. Oxid Med Cell Longev 2018; 2018: 2856063.
Akwa Y, Gondard E, Mann A, Capetillo-Zarate E, Alberdi E, Matute C, Marty S, Vaccari T, Lozano AM, Baulieu EE, Tampellini D. Synaptic activity protects against AD and FTD-like pathology via autophagic-lysosomal degradation. Mol Psychiatry 2018; 23: 1530–1540.
Rebai O, Belkhir M, Sanchez-Gomez MV, Matute C, Fattouch S, Amri M. Differential Molecular Targets for Neuroprotective Effect of Chlorogenic Acid and its Related Compounds Against Glutamate Induced Excitotoxicity and Oxidative Stress in Rat Cortical Neurons. Neurochem Res 2017; 42: 3559–3572.
Pérez-Samartín A, Garay E, Moctezuma JPH, Cisneros-Mejorado A, Sánchez-Gómez MV, Martel-Gallegos G, Robles-Martínez L, Canedo-Antelo M, Matute C, Arellano RO. Inwardly Rectifying K+ Currents in Cultured Oligodendrocytes from Rat Optic Nerve are Insensitive to pH. Neurochem Res 2017; 42: 2443–2455.
Fattorini G, Melone M, Sánchez-Gómez MV, Arellano RO, Bassi S, Matute C, Conti F. GAT-1 mediated GABA uptake in rat oligodendrocytes. Glia 2017; 65: 514–522.
Cipriani R, Chara JC, Rodríguez-Antigüedad A, Matute C. Effects of FTY720 on brain neurogenic niches in vitro and after kainic acid-induced injury. J Neuroinflammation 2017; 14: 147.
Cavaliere F, Cerf L, Dehay B, Ramos-Gonzalez P, De Giorgi F, Bourdenx M, Bessede A, Obeso JA, Matute C, Ichas F, Bezard E. In vitro α-synuclein neurotoxicity and spreading among neurons and astrocytes using Lewy body extracts from Parkinson disease brains. Neurobiol Dis 2017; 103: 101–112.